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Information About the Disease
Acromegaly is a chronic disease characterized by enlargement of the bones of the head, hands, and feet, and swelling and enlargement of soft tissue. It is caused by excessive secretion of growth hormone (GH) by the pituitary gland. This increased and unregulated GH production is usually caused by a GH-secreting pituitary tumor.
Annual new patients incidence is estimated to be 3 to 4 cases per million people per year. Median age at diagnosis is 40 years in males and 45 years in females. No clear relationship exists between incidence and race. Acromegaly occurs with equal frequency in males and females. No clear gender predilection is apparent.
The goal of treatment is amelioration of symptoms caused by both the local effects of the tumor itself and excess GH production. Because elevated GH concentration is associated with increased mortality rates, treatment seeks to decrease/normalize their concentration.
For more information about the disease please visit www.hgfound.org.